Hyperthyroidism - Symptoms and Causes

Hyperthyroidism, or overactive thyroid, occurs when the thyroid gland produces too much thyroid hormone. This gland, located at the base of your neck, regulates your metabolism. Excess hormone production speeds up bodily functions, causing symptoms like weight loss, rapid heartbeat, hand tremors, and anxiety.

Common Symptoms of Hyperthyroidism

Hyperthyroidism can affect your entire body, causing:

  • Weight loss despite normal or increased appetite.
  • Fast or irregular heartbeat (tachycardia or arrhythmia).
  • Hand tremors or shakiness.
  • Nervousness, anxiety, or irritability.
  • Increased sweating and heat sensitivity.
  • Goiter (enlarged thyroid, visible at the neck base).
  • Frequent bowel movements or diarrhea.
  • Menstrual irregularities.
  • Sleep problems and fatigue.
  • Hair thinning and brittle skin.

Causes of Hyperthyroidism

Common causes include:

  • Graves’ disease: An autoimmune disorder prompting the thyroid to overproduce hormones.
  • Thyroid nodules: Noncancerous lumps in the gland that produce excess hormones.
  • Thyroiditis: Temporary inflammation of the gland, often leading to a short phase of hyperthyroidism.
  • Excess iodine: From foods, supplements, or medications.

Risk Factors of Hyperthyroidism

  • Family history of thyroid or autoimmune conditions.
  • Smoking.
  • Recent pregnancy, which can lead to postpartum thyroiditis.

When to See a Doctor 

Consult a healthcare provider if you notice:

  • Unexplained weight loss.
  • Rapid or irregular heartbeat.
  • Neck swelling or goiter.
  • Persistent sweating or heat intolerance.

Diagnosing Hyperthyroidism

Doctors use:

  1. Physical exams to check for signs like goiter or warm skin.
  2. Blood tests to measure thyroid hormone levels (T3, T4, and TSH).
  3. Imaging tests, such as radioactive iodine uptake (RAIU) or thyroid ultrasound.

Complications of Untreated Hyperthyroidism

  • Heart issues: Atrial fibrillation or congestive heart failure.
  • Brittle bones (osteoporosis): Excess hormones reduce calcium absorption into bones.
  • Vision problems: Thyroid eye disease, causing bulging eyes and light sensitivity.
  • Thyrotoxic crisis (thyroid storm): A rare but life-threatening condition requiring emergency care.

What is a Thyroid Storm?

A thyroid storm (or thyrotoxic crisis) is a rare but life-threatening condition where the thyroid gland releases a large amount of thyroid hormone suddenly. This can cause severe symptoms like high fever, a fast heartbeat, agitation, confusion, and even heart failure. It often happens in people with untreated hyperthyroidism and is usually triggered by stress or a serious illness. Immediate medical care is essential if a thyroid storm is suspected.

Key Facts About Thyroid Storm

  • Cause: Sudden, excessive release of thyroid hormones due to uncontrolled hyperthyroidism.
  • Symptoms: High fever, rapid heart rate, agitation, confusion, restlessness, tremors, nausea, vomiting, diarrhea, sweating, and bulging eyes.
  • Triggers: Major stressors like infections, surgery, trauma, or iodine exposure.
  • Urgency: It’s a medical emergency that requires immediate treatment.

If you or someone you know shows these symptoms, seek help right away!

Treatment Options for Hyperthyroidism

Treatment depends on the cause and may include:

Anti-Thyroid Medications to Block Hormone Production

Anti-thyroid medications are a primary treatment option for hyperthyroidism, offering a way to manage the condition without permanent alterations to the thyroid gland. These medications reduce the production of thyroid hormones (thyroxine/T4 and triiodothyronine/T3) by blocking the enzyme thyroid peroxidase (TPO), essential for hormone synthesis. By slowing down hormone production, they help stabilize thyroid levels, making them particularly effective for managing symptoms of hyperthyroidism while preparing for other treatments, such as surgery or radioactive iodine therapy.

The benefits of anti-thyroid medications include their non-invasive nature, reversibility, and suitability for short-term use in conditions like thyroiditis. However, regular follow-ups are crucial to monitor thyroid hormone levels, liver function, and white blood cell counts to prevent complications. Treatment duration typically lasts 12–18 months for conditions like Graves’ disease, with the possibility of remission. These medications provide a reliable, flexible approach to managing hyperthyroidism, especially when combined with careful monitoring and patient education about adherence and potential side effects.

Radioactive Iodine Therapy

RAI therapy uses radioactive iodine to target and destroy thyroid cells, with minimal impact on the rest of your body. However, you may emit small amounts of radiation that can affect others, so precautions are necessary which will be discussed prior to the RAI therapy.

Your thyroid uses iodine to make hormones, which you typically get from food and iodized salt. In RAI therapy, your thyroid absorbs radioactive iodine, which kills the thyroid cells using radiation. This treatment is a form of nuclear medicine.

This therapy is available as capsules, a drink, or an IV injection and is typically what your doctor will prescribe.

Surgery for Hyperthyroidism

Surgery is a definitive treatment option for hyperthyroidism. It involves the partial or complete removal of the thyroid gland and is typically recommended when other treatments, such as anti-thyroid medications or radioactive iodine therapy, are unsuitable or ineffective. Surgery may be preferred in cases of severe thyroid gland enlargement (goiter) causing compression symptoms, suspicion of thyroid cancer, or for patients who cannot tolerate medications. For those with Graves' disease or toxic nodular goiter, surgery provides a permanent solution, eliminating the overproduction of thyroid hormones.

The procedure is performed under general anesthesia and generally has a high success rate in resolving hyperthyroidism. However, it is not without risks. Potential complications include damage to the parathyroid glands, which can lead to calcium imbalances, or injury to the recurrent laryngeal nerve, potentially affecting the voice. Patients may also develop hypothyroidism, requiring lifelong thyroid hormone replacement therapy. Despite these risks, modern surgical techniques and skilled surgeons have minimized complications, making thyroidectomy a safe and effective option for many patients. Postoperative care and monitoring are crucial to ensure a smooth recovery and stable hormone levels.

Beta-Blockers: Symptom Management for Hyperthyroidism

Beta-blockers are commonly used in the management of hyperthyroidism to control symptoms such as a rapid heart rate, palpitations, tremors, and anxiety. These medications work by blocking the effects of adrenaline (epinephrine) on beta receptors in the heart and other parts of the body. This reduces the heart rate, lowers blood pressure, and helps alleviate the physical manifestations of hyperthyroidism, such as shakiness and nervousness.

Unlike anti-thyroid medications, beta-blockers do not affect the production or levels of thyroid hormones in the bloodstream. Their role is purely symptomatic, providing relief while the underlying thyroid dysfunction is addressed through other treatments like anti-thyroid drugs, radioactive iodine therapy, or surgery. Beta-blockers are often used as a temporary measure during the early stages of treatment when hormone levels are still high or in acute situations like a thyroid storm. While generally well-tolerated, beta-blockers may cause side effects such as fatigue, dizziness, or cold extremities and are not suitable for individuals with certain conditions, like asthma.

Can Homeopathic Remedies Help?

Homeopathic remedies are often sought as complementary or alternative treatments for hyperthyroidism. While it could provide symptom relief with homeopathic approaches, it's essential to recognize the limitations when managing a complex condition like hyperthyroidism. Homeopathy focuses on the principle of "like cures like," using highly diluted substances to stimulate the body’s natural healing processes. However, these remedies are not scientifically proven to directly address the overproduction of thyroid hormones or treat the underlying causes of hyperthyroidism.

Potential Role of Homeopathy

Some homeopathic practitioners may suggest remedies tailored to individual symptoms, such as anxiety, restlessness, or heart palpitations, which are common in hyperthyroidism. A homeopathic practitioner will talk with you and ask questions then base a remedy on that initial conversation. Typically meeting a month later to see how symptoms and you are doing.

My Experience with Homeopathy for Hyperthyroidism

I tried the homeopathy route as I really didn't want to lose a body part (no matter how small or big), and my remedy was tailored to my individual issues (or symptoms) which only consisted of a few things. I met with a Homeopathic Practitioner, they asked me all the questions and determined what the homeopathic remedy I would take. I tried this for a few months or so. Took my remedy three times a day - I honestly did feel better, but when I went back to the doctors office a few months later to get a blood test, my thyroid numbers were double. I am pretty healthy and I use remedies in my daily life, unfortunately, this may have been a bigger issue for it to work.

Homeopathy Considerations

While homeopathic remedies are generally considered safe due to their highly diluted nature, relying solely on them to manage hyperthyroidism could delay effective treatment and potentially worsen the condition. Uncontrolled hyperthyroidism can lead to serious complications, including heart issues and osteoporosis. Therefore, any use of homeopathy should be complementary to conventional medical care (such as it may help before and after medical treatment) and done under the guidance of a healthcare professional knowledgeable about thyroid disorders.

In summary, while homeopathy may offer symptom relief for some people, it is not a proven or standalone treatment for hyperthyroidism. Close monitoring and collaboration with a healthcare provider are crucial to ensure safe and effective management of the condition.

Living with Hyperthyroidism

With proper treatment, most people manage their condition well and live healthy lives. Regular follow-up is essential to monitor thyroid function and adjust treatment as needed. If untreated, hyperthyroidism can worsen and lead to severe complications. Early diagnosis and intervention can help restore balance and improve quality of life.

Related

Mayo Clinic Hyperthyroidism

American Thyroid Association on Hyperthyroidism

Healthline - Controlling Hyperthyroidism Naturally

National Library of Medicine Thyroid Storm